By Wolfsberg Tyra G., Wetterstrand Kris A., Guyer Mark S., Collins Francis S., Baxevanis Andreas D.
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Extra info for A user's guide to the human genome
To obtain more details on this hit, click the details link, to the left of the entry. A long web page is returned, with three major sections: the mRNA sequence (Fig. 5, top), the genomic sequence (Fig. 5, middle) and an alignment of the mRNA sequence against the genomic sequence (see Fig. 9 for an example). In the alignment in Fig. 5, matching bases in the cDNA and genomic sequences are colored in darker blue and capitalized. Gaps are indicated in lower-case black type. Light blue upper-case bases mark the boundaries of aligned regions on either side of a gap and are often splice sites.
Edu), click on Browser in the blue sidebar on the left-hand side of the page, and set the Genome Browser Gateway to a region of interest. For example, one could set the genome to Human and the assembly to Dec. 2001, type chr22:38496887-39496866 into the position box, and click Submit to display a representative region of the December 2001 assembly of human chromosome 22. A number of tracks are already displayed in dense format (Fig. 1). Below the graphic showing the specified region are pull-down menus that allow the user to change the appearance of the graphic, under the heading Track Controls (Fig.
Most of the methods show a 3′ untranslated region, indicated by the heavy, shorter block at the left of the predictions. The Acembly track shows three possible alternative splices in addition to the full-length product shown in the third line of that section, a prediction that agrees with those shown in most of the other tracks. The Genscan track extends off to both the right and the left: GENSCAN can be used to predict multiple genes, and this display implies that the method has been applied in this fashion.